08-19-2006, 12:39 PM
http://www.autism speaks.org/science/chromosome_15.php
Anyone interested, they are trying to explain the role of chromosome 15 in Autism.
Anyone interested, they are trying to explain the role of chromosome 15 in Autism.
08-19-2006, 12:39 PM
08-19-2006, 04:49 PM
The link isn't working for me. 
08-19-2006, 06:50 PM
Did you remove the spaces? It worked for me.
08-19-2006, 08:47 PM
:roll: They're still not recognizing the spectrum. I really shouldn't be so surprised.
08-20-2006, 01:01 PM
Doh, I didn't realize it was a broken link. :roll:
Okay, read it now. I find it interesting that they think this could be something big with regards to Autism and that it's a maternally-derived duplication; however, there's more males (i.e., fathers) out there passing on the lineage than mothers I'd imagine.
However, with what they noted about GABA being controlled for on chr. 15, that makes sense. We do definitely have GABA problems-- which is why we're so prone to seizures as well...
About a year ago I read a research article finding similarities between those with Williams' Syndrome and Autistic Disorder and the splinter skills that often accompany both disorders and that one of the chromosomal abnormalities they might have in common would be chr. 15.
Okay, read it now. I find it interesting that they think this could be something big with regards to Autism and that it's a maternally-derived duplication; however, there's more males (i.e., fathers) out there passing on the lineage than mothers I'd imagine.
However, with what they noted about GABA being controlled for on chr. 15, that makes sense. We do definitely have GABA problems-- which is why we're so prone to seizures as well...
About a year ago I read a research article finding similarities between those with Williams' Syndrome and Autistic Disorder and the splinter skills that often accompany both disorders and that one of the chromosomal abnormalities they might have in common would be chr. 15.
08-22-2006, 02:10 PM
Too simplistic. It ignores a lot of research in the field on other loci and chromosomes.
We're looking at the new thimerosol.
We're looking at the new thimerosol.
08-23-2006, 12:38 AM
Dogface Wrote:
Too simplistic. It ignores a lot of research in the field on other loci and chromosomes.
We're looking at the new thimerosol.
We're looking at the new thimerosol.
In the Spectrum which they're already aware probably includes a huge number of genes on many chromosomes, focusing on any one chromosome would be too simplistic.
I'm not sure that's the point of the article though, to explain the whole Spectrum or even a disorder in certain families, due solely to chr. 15. But it's possible chr. 15 is a very important and far-reaching gene in many cases on the Spectrum, despite that other disorders might be completely contained on that chromosome.
At least that's how I read the article.