Aspies For Freedom

http://www.msnbc.msn.com/id/11080815/site/newsweek/

I did not cut the whole article as it is very long.  When I read the paragraph below, something struck me . It mentioned how groups that are close genetically and marry within the group suffer from diseases that are not bred out  by intermarriage  with other groups.  So if a genetic group that intermarries a lot has this issue. I was thinking about aspergians who intermarry with them selves and NTs with traits/no traits that we see LFA. I am wondering a lot the negative comorbids/aspects arent just  like  taysachs for ashekanzi jews. In other words we are a seperate ethnicity that has issues due to the high common genetic mix within the group.
Also it would be we are descended from a small group in the past.

[quote]The mutations in our DNA not only point to long-lost ancestors and homelands, they may also be markers for genetic disease. It's known as the founder effect: populations with marked susceptibilities to certain illnesses tend to be descended from a small group of ancestors who bred only within their own community. Sticking together meant a higher chance of inheriting a disease. The Amish, for example, are more likely to carry a genetic mutation for a condition called polydactyly, which causes extra fingers or toes. Ashkenazi Jews have an unusually high risk of certain cancers, as well as Gaucher and Tay-Sachs diseases. Men and women who inherit the mutation that causes Tay-Sachs are unaffected, but if they mate, they have a one-in-four chance of having an afflicted child. That's why Jewish parents-to-be are offered a panel of genetic tests before conceiving.[/qoute]

I was thinking about aspergians who intermarry with them selves and NTs with traits/no traits that we see LFA.

Where have you seen that? I have not seen any statistics that seem to present that. Or is it anecdotal?
The anecdotal things that I have heard do not show that two aspies, or aspie types have LFA children.
I know a couple and the man is an aspie and the girl is autistic, and they have an NT daughter.
Of course two aspies could have an LFA child, but it seems that two NTs could too.
And LFA kids can develop and be called HFA, but the terms are deceptive anyway if its taken in terms of IQ.

Classifications like "LFA" have been invented by and for the use of NTs and tell us nothing about autistic people. They describe only the perceptions and expectations of us held by NTs, and as such they stigmatize.

Well, I once read an article (and now please forgive my english, for I'm defenitely not good at scientific vocabulary) about special types of people who marry and might have a risk of having kids on the spectrum.

It was about parents who were quite well educated with gifts in mathematics or nature science and the author of the article thought that those gifts came from being able to classify things and finding patterns. And if people with those gifts would have children, the probability of having autistic kids would rise, for they'd inherit that pattern-finding from their parents. And that pattern-thing being too much would make them be on the spectrum.

Hope this wasn't too confused.

Sibylle

Atreus's article is mostly talking about genes with a single sequence variation that screws up the function of the protein the gene makes, like by making a defective enzyme that can't do what it's supposed to do (e.g. Tay-Sachs--see http://www.marchofdimes.com/professionals/681_1227.asp)

It is likely that a complex neurobiological mindset like autism results from the action of multiple genes, genes that occur in everyone but which might, in autism, have minor variations or which are present in more or less amounts such that neuro-develpment is affected.  As best I can discern from reading around, no clear correlations between the action of any specific gene and autism have been uncovered and substantiated.